Full course description

MiniCourse Overview

This MiniCourse is self-paced and takes 3 to 5 hours to complete. At the end of this MiniCourse you will have examined the historical context that led to the mouse becoming the preeminent animal model system. You will receive a certificate and digital badge for completing the MiniCourse. In order to claim a certificate or badge for this MiniCourse, you must go through the Core Content module and take the self-review quiz (scoring at least 70%).

The following topics will be discussed:

  • Phylogenetic history of Mus and laboratory strains
  • Classical 19th century genetics
  • The Jackson Laboratory and the inbred mouse
  • Landmark classical experiments in mouse genetics
  • Latest genetic and genomic research discoveries
Learning Outcomes

By the end of the MiniCourse, you will be able to:

1. Examine evolutionary origins of the laboratory mouse 
2. Outline the history of inbred mouse line
3. Identify instrumental mouse genetic discoveries that helped build the biomedical tool box
4. Outline the advent of knockout, transgenic and knockin model systems
5. Point out advances leading to CC, DO and PDX mouse models (the current models)
6. Appraise readings with historical perspectives on mouse genetics (optional)

Target Audience

This MiniCourse is designed to meet the needs of graduate and post-doctoral students, research assistants, advanced undergraduate students, and advanced animal care technicians.


About our Education Offerings

Founded in 1929, The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 1,800 employees who are passionate about our mission: to discover precise genomic solutions for disease and to empower the global biomedical community in the shared quest to improve human health.

While we are not an accredited higher education institution, we offer a variety of education programs — including our non-credit bearing MiniCourses and Certificates — designed to educate current and future scientists and to provide critical resources, data, tools, and services to researchers worldwide.

MiniCourses are created and reviewed by multiple JAX faculty, scientists, educators, and other experts, and include interactive content based on the live lectures delivered in our on-campus Courses, Conferences, and Workshops.

MiniCourses are available to learners individually and in topical Certificate Program collections, which are organized around both foundational content and the research areas in which The Jackson Laboratory has earned a reputation for scientific leadership and excellence.


Hardware and Software Requirements
  • Audio speakers or headphones
  • Screen resolution of 800X600 or higher
  • Adobe Reader 5.0 or higher
  • JavaScript enabled
  • 1GB of RAM
  • 2GHz processor
Check the basic computer specifications and supported browsers.