Full course description
This course has been moved to a new learning platform in order to provide you with an even better online learning experience! Register in the new version of this course >>
Already enrolled or want to download your certificate? Access your Canvas dashboard directly here until June 30, 2022.
About this Course
Pediatric neurology providers and patients have more options than ever before for genetic testing. Evidence is growing for the utility of genetic testing for a range of conditions for the purpose of diagnosis and optimizing treatment. While genetic testing can be a powerful tool in certain situations, not all genetic testing is the same. Broader tests assess more genes and increase the possibility of a diagnosis, but also confer specific benefits, limitations, and challenges in results interpretation and counseling.
Precision Medicine for Your Practice is a series of short (20-30 min), online modules covering specific topics in genomics and precision medicine. In this module, Genetic Testing in Pediatric Neurology, participants will learn the benefits and limitations of genetic testing for pediatric neurological conditions. This online module will include five parts: overview information via an animated video; practice cases to facilitate learning-by-doing; and "dig deeper," logistics, and additional resources for those who are interested in more detail.
Already enrolled? Access the course directly here.
Precision Medicine For Your Practice: Genetic Testing in Pediatric Neurology - CME
Original Publication Date: September 5, 2019
Expiration Date: September 4, 2022
Upon completion of this educational activity, the physician will be able to:
- Identify scenarios in which there is further value added by molecular diagnosis
- Evaluate the appropriateness of different genetic tests for clinical context
This activity is designed to meet the educational needs of practicing physicians who work with children with neurologic conditions.
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
Credit Designation Statement
The American Medical Association designates this enduring material for a maximum of .50 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Claiming Your CME Credit
In order to claim AMA PRA Category 1 Credit™, you must: 1) answer the pre-assessment questions, 2) work through the module in its entirety, 3) successfully complete the post-assessment by answering 4 out of 5 questions correctly and 4) complete the evaluation.
Emily Edelman, MS, CGC, Associate Director, Clinical and Continuing Education, The Jackson Laboratory
Kate Reed, MPH, ScM, CGC, Director, Clinical and Continuing Education, The Jackson Laboratory
Therese Ingram Nissen, MA, Senior Instructional Designer/Technologist, The Jackson Laboratory
Sean C. McConnell, PhD, Senior Policy Analyst, Science, Medicine & Public Health, CME Program Committee, AMA
Laura Nicholson, MD, PhD, Director of Education, Scripps Research Translational Institute
Unless noted, no individuals in control of content reported a conflict of interest.
Baker E, Jeste S. Diagnosis and Management of Autism Spectrum Disorder in the Era of Genomics Rare Disorders Can Pave the Way for Targeted Treatments. Pediatr Clin North Am. 2015;62:607-618.
Bello L, Pegoraro E. Genetic diagnosis as a tool for personalized treatment of Duchenne muscular dystrophy. Acta Myol. 2016;35(3):122-127.
Bird TD. Approaches to the Patient with Neurogenetic Disease. Clin Lab Med. 2010;30:785-793.
Demarest ST, Brooks-Kayal A. From molecules to medicines: the dawn of targeted therapies for genetic epilepsies. Nat Rev Neurol. 2018;14(12):735-745.
Dowling JJ, D Gonorazky H, Cohn RD, Campbell C. Treating pediatric neuromuscular disorders: The future is now. Am J Med Genet A. 2018;176(4):804-841.
Fogel BL. Genetic and genomic testing for neurologic disease in clinical practice. Handb Clin Neurol. 2018;147:11-22.
Fogel BL, Saty Satya-Murti, Cohen BH. Clinical exome sequencing in neurologic disease. Neurol Clin Pr. 2016;6:164-176.
Huang Y, Yu S, Wu Z TB. Genetics of hereditary neurological disorders in children. Transl Pediatr. 2014;3(2):108-119.
Kang PB. Ethical issues in neurogenetic disorders. Ethical Leg Issues Neurol. 2013;118:265-276.
Kaufmann WE. Neurogenetics in Child Neurology: Redefining a Discipline in the Twenty-first Century. Curr Neurol Neurosci Rep. 2016;16:103.
Kiely B, Vettam S, Adesman A. Utilization of genetic testing among children with developmental disabilities in the United States. Appl Clin Genet. 2016;9:93-100.
Narayanan V. Genetics and Child Neurology: What Every Trainee/Resident Should Know. Semin Pediatr Neurol. 2011;18:81-84.
Neubauer BA, Lemke JR. From Genetics to Genomics: A Short Introduction for Pediatric Neurologists. Neuropediatrics. 2016;47:5-11.
Ream MA, Patel AD. Obtaining genetic testing in pediatric epilepsy. Epilepsia. 2015;56(10):1505-1514.
Silveira-Moriyama L, Paciorkowski AR. Genetic Diagnostics for Neurologists. Contin Lifelong Learn Neurol. 2018;24(1):18-36.
Sisodiya SM. Genetic screening and diagnosis in epilepsy? Curr Opin Neurol. 2015;28(2):136-142.
Tarailo-Graovac M, Shyr C, Ross CJ, et al. Exome Sequencing and the Management of Neurometabolic Disorders. N Engl J Med. 2016;374:2246-2255.
Vento JM. Family History: A Guide for Neurologists in the Age of Genomic Medicine. Semin Pediatr Neurol. 2012;19:160-166.
Audio speakers or headphones
Screen resolution of 800X600 or higher
Adobe Reader 5.0 or higher
For best performance in a mobile environment, please download the Canvas Mobile App for IOS and Android.
Should you have technical questions or questions regarding the content of the activity, please email Clinical and Continuing Education at the Jackson Laboratory.
All information in Precision Medicine for Your Practice is provided for educational purposes only. This information is not a substitute for clinical guidance or the consultation of a medical professional. Always seek the advice of a qualified health professional with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read in Precision Medicine for Your Practice. Reliance on any information in Precision Medicine for Your Practice is solely at your own risk. The Jackson Laboratory does not endorse or recommend any specific procedures, tests, products, services, health professionals or other information that may be found in Precision Medicine for Your Practice.